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Biological Activity
KX2-391 2Hcl is the first clinical Src inhibitor (peptidomimetic class) that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.82 mL | 99.12 mL | 198.24 mL |
| 0.5 mM | 3.96 mL | 19.82 mL | 39.65 mL |
| 1 mM | 1.98 mL | 9.91 mL | 19.82 mL |
| 5 mM | 0.4 mL | 1.98 mL | 3.96 mL |
*The above data is based on the productmolecular weight 504.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11471 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1038395-65-1 |
| Formula | C26H31Cl2N3O3 |
| M. Wt | 504.45 |
| Purity | >98% |
| Synonyms | KX2-391 2HCl, KX2-391 |
| SMILES | C1COCCN1CCOC2=CC=C(C=C2)C3=CN=C(C=C3)CC(=O)NCC4=CC=CC=C4.Cl.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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