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LD-38

Catalog No.: A41595
Drug-Linker Conjugate for ADC
LD-38 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It combines a topoisomerase I inhibitor, Exatecan, with a stable, cleavable linker that enhances hydrophilicity. This compound is ideal for the synthesis of various ADCs, including KA-3123-LD38, and is utilized in research focusing on targeted cancer therapies and drug delivery systems.
LD-38 3094583-35-1 Drug-Linker Conjugate for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLD-38 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It combines a topoisomerase I inhibitor, Exatecan, with a stable, cleavable linker that enhances hydrophilicity. This compound is ideal for the synthesis of various ADCs, including KA-3123-LD38, and is utilized in research focusing on targeted cancer therapies and drug delivery systems.
Product Information
Catalog NumA41595
FormulaC67H87FN10O20S
Molecular Weight1403.53
CAS Number3094583-35-1
SMILESO=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](C(NC2=CC=C(COC(N[C@H]3CCC(C(C)=C(F)C=C4N=C5C6=CC7=C8COC([C@](CC)7O)=O)=C4C3=C5CN6C8=O)=O)C=C2)=O)CCC(NCC[N+](C)(CCCS([O-])(=O)=O)C)=O)=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC