Lenvatinib mesylate

Catalog No.: A17567

multi-targeted tyrosine kinase inhibitor

Lenvatinib mesylate

Lenvatinib mesylate Chemical Structure

CAS NO. 857890-39-2

Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities.

Availability: In stock

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1 mg

Regular Price: $320.00

Special Price $256.00

5 mg

Regular Price: $960.00

Special Price $768.00

10 mg

Regular Price: $1,600.00

Special Price $1,280.00

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Biological Activity

Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities.
In vitro DMSO 34 mg/mL (65.01 mM)
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.12 mL 95.61 mL 191.22 mL
0.5 mM 3.82 mL 19.12 mL 38.24 mL
1 mM 1.91 mL 9.56 mL 19.12 mL
5 mM 0.38 mL 1.91 mL 3.82 mL

*The above data is based on the productmolecular weight 522.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17567
Actions Inhibitor
CAS No. 857890-39-2
Formula C22H23ClN4O7S
M. Wt 522.96
Purity >98%
Synonyms E7080 mesylate, E 7080, E-7080
SMILES O=C(C1=C(OC)C=C2N=CC=C(OC3=CC=C(NC(NC4CC4)=O)C(Cl)=C3)C2=C1)N.OS(=O)(C)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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