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LFM-A13 is a potent and selective inhibitor of Btk with IC50 of 17.2 uM; also inhibits PLK3 with IC50 of 7.2 uM.
Targets
| BTK | ||||
| 2.5 μM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.78 mL | 138.89 mL | 277.78 mL |
| 0.5 mM | 5.56 mL | 27.78 mL | 55.56 mL |
| 1 mM | 2.78 mL | 13.89 mL | 27.78 mL |
| 5 mM | 0.56 mL | 2.78 mL | 5.56 mL |
*The above data is based on the productmolecular weight 360. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A16261 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 360 |
| Formula | C11H8Br2N2O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 244240-24-2 |
| Synonyms | LFM A13 |
| SMILES | C/C(O)=C(/C(O)=N/C1=C(Br)C=CC(Br)=C1)C#N |
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