LOXO-101 (ARRY-470, Larotrectinib)

Catalog No.: A15974
TRK inhibitor
LOXO-101 is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC.
Grouped product items
Product Name Price Stock Qty
LOXO-101 (ARRY-470) 5mg
In stock
LOXO-101 (ARRY-470) 10mg
In stock
LOXO-101 (ARRY-470) 50mg
In stock

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription LOXO-101 is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC.
Target Value
Chemical Information
Catalog Num A15974
Formula C21H22F2N6O2
Molecular Weight 428.44
CAS Number 1223403-58-4
Synonyms LOXO 101, LOXO101, ARRY470, ARRY 470

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro DMSO 85 mg/mL (198.39 mM)
Water Insoluble
Ethanol 85 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.34 mL 116.7 mL 233.4 mL
0.5 mM 4.67 mL 23.34 mL 46.68 mL
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL
Useful Calculator

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