LOXO-101 sulfate

Catalog No.: A16239

TRK inhibitor

LOXO-101 sulfate

LOXO-101 sulfate Chemical Structure

CAS NO. 1223405-08-0

LOXO-101 is a small molecule that was designed to block the ATP binding site of the TRK family of receptors, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.

Availability: In stock

Package Price Qty
5 mg
$320.00
10 mg
$480.00
50 mg
$1,400.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

LOXO-101 is a small molecule that was designed to block the ATP binding site of the TRK family of receptors, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.
Targets
TRK
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.99 mL 94.96 mL 189.93 mL
0.5 mM 3.8 mL 18.99 mL 37.99 mL
1 mM 1.9 mL 9.5 mL 18.99 mL
5 mM 0.38 mL 1.9 mL 3.8 mL

*The above data is based on the productmolecular weight 526.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A16239
Actions Inhibitor
M. Wt 526.51
Formula C21H24F2N6O6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1223405-08-0
Synonyms LOXO101 sulfate, LOXO 101 sulfate
SMILES C1CC(N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CCC(C4)O)C5=C(C=CC(=C5)F)F.OS(=O)(=O)O

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