LY 2874455

Catalog No.: A11244

FGFR/VEGFR2 inhibitor

LY 2874455 Chemical Structure

CAS NO. 1254473-64-7

LY2874455 is a novel and potent FGFR/VEGFR Inhibitor.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
25 mg
$360.00
50 mg
$680.00
10mM * 1mL in DMSO
$140.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

LY2874455 is a novel and potent FGFR/VEGFR Inhibitor.
Targets
FGFR2 FGFR1 FGFR4 FGFR3 VEGFR2
2.6 nM2.8 nM6 nM6.4 nM7 nM
In vitro DMSO 88 mg/mL (198.05 mM)
Water <1 mg/mL (<1 mM)
Ethanol 88 mg/mL heating (198.05 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.51 mL 112.53 mL 225.07 mL
0.5 mM 4.5 mL 22.51 mL 45.01 mL
1 mM 2.25 mL 11.25 mL 22.51 mL
5 mM 0.45 mL 2.25 mL 4.5 mL

*The above data is based on the productmolecular weight 444.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11244
Actions Inhibitor
M. Wt 444.31
Formula C21H19Cl2N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1254473-64-7
Synonyms LY-2874455, LY2874455
SMILES C[[email protected]](C1=C(C=NC=C1Cl)Cl)OC2=CC3=C(C=C2)NN=C3/C=C/C4=CN(N=C4)CCO

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