LY2801653 (Merestinib)

Catalog No.: A12557

c-MET inhibitor

LY2801653 (Merestinib)

LY2801653 (Merestinib) Chemical Structure

CAS NO. 1206799-15-6

LY2801653 is a potent, orally bioavailable, small-molecule inhibitor of c-MET kinase(Ki= 2 nM).

Availability: In stock

Package Price Qty
5 mg

Regular Price: $100.00

Special Price $90.00

10 mg

Regular Price: $150.00

Special Price $135.00

50 mg

Regular Price: $450.00

Special Price $405.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

LY2801653 is a potent, orally bioavailable, small-molecule inhibitor of c-MET kinase(Ki= 2 nM).
Targets
Met
2 nM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.1 mL 90.49 mL 180.99 mL
0.5 mM 3.62 mL 18.1 mL 36.2 mL
1 mM 1.81 mL 9.05 mL 18.1 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 552.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12557
Actions Inhibitor
M. Wt 552.53
Formula C30H22F2N6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1206799-15-6
Synonyms LY-2801653, Merestinib
SMILES O=C(C1=CC=C(C)N(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=CC5=C(N(C)N=C5)C=C4C6=CNN=C6)C(F)=C3

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