LY2801653 (Merestinib)
LY2801653 is a potent, orally bioavailable, small-molecule inhibitor of c-MET kinase(Ki= 2 nM).
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Adooq Products cited in reputable paper
Adooq's LY2801653 (Merestinib) has been cited by 1 publications
- Ji-Eun Kim, .et al. , Immunity, 2022, Dec 13;55(12):2300-2317 PMID: 36473468
Biological Activity
| Description | LY2801653 is a potent, orally bioavailable, small-molecule inhibitor of c-MET kinase(Ki= 2 nM). | ||
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Product Information
| Catalog Num | A12557 |
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| Formula | C30H22F2N6O3 |
| Molecular Weight | 552.53 |
| CAS Number | 1206799-15-6 |
| SMILES | O=C(C1=CC=C(C)N(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=CC5=C(N(C)N=C5)C=C4C6=CNN=C6)C(F)=C3 |
| Synonyms | LY-2801653, Merestinib |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 88 mg/mL (159.26 mM) | |
| Water | Insoluble | ||
| Ethanol | 88 mg/mL | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.1 mL | 90.49 mL | 180.99 mL |
| 0.5 mM | 3.62 mL | 18.1 mL | 36.2 mL |
| 1 mM | 1.81 mL | 9.05 mL | 18.1 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
