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Lys-Nε-SPDB-DM4

Catalog No.: A41477
Drug-Linker Conjugates for ADC
Lys-Nε-SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound combines the potent tubulin inhibitor DM4 with the Lys-Nε-SPDB linker to facilitate targeted delivery and enhanced therapeutic efficacy. Lys-Nε-SPDB-DM4 is suitable for research focused on cancer therapeutics, particularly in studies investigating the mechanisms of action and optimization of ADCs.
Lys-Nε-SPDB-DM4 1280215-91-9 Drug-Linker Conjugates for ADC
Grouped product items
Size Price Stock Qty
1mg
$450.00
In stock
5mg
$1,150.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLys-Nε-SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound combines the potent tubulin inhibitor DM4 with the Lys-Nε-SPDB linker to facilitate targeted delivery and enhanced therapeutic efficacy. Lys-Nε-SPDB-DM4 is suitable for research focused on cancer therapeutics, particularly in studies investigating the mechanisms of action and optimization of ADCs.
Product Information
Catalog NumA41477
FormulaC48H72ClN5O13S2
Molecular Weight1026.69
CAS Number1280215-91-9
SMILESC[C@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C(CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CCC(C)(C)SSCCCC(NCCCC[C@H](N)C(O)=O)=O)=O)=O)=O)C)=C(C(OC)=C4)Cl)\C)OC)(NC(O3)=O)O)C)([H])O1
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC