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m-PEG8-Lys(Mal)-Val-Ala-PAB-Ph-CO-Dazostinag

Catalog No.: A41534
Drug-Linker Conjugates for ADC
m-PEG8-Lys(Mal)-Val-Ala-PAB-Ph-CO-Dazostinag is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound facilitates targeted delivery of cytotoxic agents, enhancing therapeutic efficacy while minimizing off-target effects. It combines a polyethylene glycol (PEG) spacer with a maleimide reactive group, allowing for efficient conjugation to antibodies, making it valuable for researchers developing novel ADCs for targeted cancer therapies.
m-PEG8-Lys(Mal)-Val-Ala-PAB-Ph-CO-Dazostinag 2553413-13-9 Drug-Linker Conjugates for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionm-PEG8-Lys(Mal)-Val-Ala-PAB-Ph-CO-Dazostinag is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound facilitates targeted delivery of cytotoxic agents, enhancing therapeutic efficacy while minimizing off-target effects. It combines a polyethylene glycol (PEG) spacer with a maleimide reactive group, allowing for efficient conjugation to antibodies, making it valuable for researchers developing novel ADCs for targeted cancer therapies.
Product Information
Catalog NumA41534
FormulaC74H98F2N14O27P2S2
Molecular Weight1779.72
CAS Number2553413-13-9
SMILESO=C(C=C1)N(CCCC[C@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)C(N[C@@H](C(C)C)C(N[C@@H](C)C(NC2=CC=C(COC(N(C)CC3=C(C(NC4=C(N=CN5[C@@H]6O[C@H](CO[P@]7(S)=O)[C@@H](O[P@@](OC[C@@H]8[C@@H](O)[C@@H](O7)[C@H](N9C(N=CNC%10=O)=C%10C(F)=C9)O8)(S)=O)[C@H]6F)C5=NC=N4)=O)C=CC=C3)=O)C=C2)=O)=O)=O)C1=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC