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Mal-C2-Gly3-EDA-PNU-159682

Catalog No.: A41406
Drug-Linker Conjugates for ADC
Mal-C2-Gly3-EDA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound features a cleavable linker, Mal-C2-Gly3-EDA, which facilitates the targeted delivery of the cytotoxic agent PNU-159682 to specific cells. Its robust structure allows for effective release of the potent cytotoxin upon internalization, making it suitable for cancer research and therapeutic development in targeted therapies.
Mal-C2-Gly3-EDA-PNU-159682 2259318-53-9 Drug-Linker Conjugates for ADC
Grouped product items
Size Price Stock Qty
1mg
$530.00
In stock
5mg
$1,225.00
In stock
10mg
$2,010.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-C2-Gly3-EDA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound features a cleavable linker, Mal-C2-Gly3-EDA, which facilitates the targeted delivery of the cytotoxic agent PNU-159682 to specific cells. Its robust structure allows for effective release of the potent cytotoxin upon internalization, making it suitable for cancer research and therapeutic development in targeted therapies.
Product Information
Catalog NumA41406
FormulaC46H53N7O18
Molecular Weight991.95
CAS Number2259318-53-9
SMILESO=C([C@@]1(O)C[C@H](O[C@H]2C[C@@]3([H])[C@]([C@H](C)O2)([H])O[C@]4([H])[C@@H](OC)OCCN43)C5=C(O)C6=C(C(C7=CC=CC(OC)=C7C6=O)=O)C(O)=C5C1)NCCNC(CNC(CNC(CNC(CCN8C(C=CC8=O)=O)=O)=O)=O)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC