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Mal-(CH2)5-Val-Cit-PAB-Eribulin

Catalog No.: A41333
Drug-Linker Conjugate for ADC
Mal-(CH2)5-Val-Cit-PAB-Eribulin is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, targeting microtubules to exert potent antitumor effects. The compound features the anti-microtubule agent Eribulin, which is covalently linked via the Mal-(CH2)5-Val-Cit-PAB linker. This strategic design enhances the therapeutic efficacy of Eribulin while minimizing systemic toxicity, making it a valuable tool for cancer research and development.
Mal-(CH2)5-Val-Cit-PAB-Eribulin 2130869-21-3 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
1mg
$250.00
In stock
5mg
$665.00
In stock
10mg
$1,310.00
In stock
25mg
$2,015.00
In stock
50mg
$3,035.00
In stock
100mg
$4,480.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-(CH2)5-Val-Cit-PAB-Eribulin is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, targeting microtubules to exert potent antitumor effects. The compound features the anti-microtubule agent Eribulin, which is covalently linked via the Mal-(CH2)5-Val-Cit-PAB linker. This strategic design enhances the therapeutic efficacy of Eribulin while minimizing systemic toxicity, making it a valuable tool for cancer research and development.
Product Information
Catalog NumA41333
FormulaC69H97N7O19
Molecular Weight1328.54
CAS Number2130869-21-3
SMILESC=C1C[C@](O[C@@]1([H])CC[C@](C[C@H]2C)([H])O[C@](C2=C)([H])C[C@@](O[C@@H]3C[C@H](O)CNC(OCC(C=C4)=CC=C4NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN(C5=O)C(C=C5)=O)=O)=O)=O)=O)([H])[C@]([C@H]3OC)([H])CC6=O)([H])CC[C@@]7(C[C@@]8([H])O9)O[C@]([C@](O[C@](C6)([H])CC%10)([H])[C@@]%10([H])O%11)([H])[C@@]9([H])[C@]%11([H])[C@@]8([H])O7
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC