Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This reagent facilitates targeted delivery of the potent antitumor antibiotic Duocarmycin SA through its unique linker structure, Mal-PEG4-VC-PAB-DMEA-Seco. Its primary mechanism involves the selective release of the cytotoxic agent upon cellular internalization, thereby enhancing therapeutic efficacy while minimizing off-target effects. This product is suitable for cancer research focused on developing and optimizing ADCs for improved clinical outcomes.
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This reagent facilitates targeted delivery of the potent antitumor antibiotic Duocarmycin SA through its unique linker structure, Mal-PEG4-VC-PAB-DMEA-Seco. Its primary mechanism involves the selective release of the cytotoxic agent upon cellular internalization, thereby enhancing therapeutic efficacy while minimizing off-target effects. This product is suitable for cancer research focused on developing and optimizing ADCs for improved clinical outcomes.
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