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Mal-Phe-C4-VC-PAB-MMAE

Catalog No.: A41404
Drug-Linker Conjugates for ADC
Mal-Phe-C4-VC-PAB-MMAE is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound features monomethyl auristatin E (MMAE), a potent inhibitor of tubulin polymerization, which serves as the cytotoxic payload. Its structure is optimized for effective delivery and targeted therapy in cancer research, making it an essential reagent for developing and studying ADCs.
Mal-Phe-C4-VC-PAB-MMAE 2259318-51-7 Drug-Linker Conjugates for ADC
Grouped product items
Size Price Stock Qty
5mg
$470.00
In stock
10mg
$775.00
In stock
25mg
$1,545.00
In stock
50mg
$2,425.00
In stock
100mg
$3,775.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-Phe-C4-VC-PAB-MMAE is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound features monomethyl auristatin E (MMAE), a potent inhibitor of tubulin polymerization, which serves as the cytotoxic payload. Its structure is optimized for effective delivery and targeted therapy in cancer research, making it an essential reagent for developing and studying ADCs.
Product Information
Catalog NumA41404
FormulaC72H105N11O15
Molecular Weight1364.67
CAS Number2259318-51-7
SMILESO[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@@]([C@@H](C)CC)([H])N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC4=CC=C(N5C(C=CC5=O)=O)C=C4)=O)=O)=O)C=C3)=O)=O)=O)=O)OC)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC