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Mal-PNU-159682

Catalog No.: A41598
Drug-Linker Conjugates for ADC
Mal-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) formulations. This compound consists of a maleimide linker combined with the cytotoxic agent PNU-159682, exhibiting significant anti-tumor activity. Its applications include enhancing the targeted delivery of therapeutics in cancer research and improving the efficacy of cancer treatment through ADC technology.
Mal-PNU-159682 1204819-90-8 Drug-Linker Conjugates for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) formulations. This compound consists of a maleimide linker combined with the cytotoxic agent PNU-159682, exhibiting significant anti-tumor activity. Its applications include enhancing the targeted delivery of therapeutics in cancer research and improving the efficacy of cancer treatment through ADC technology.
Product Information
Catalog NumA41598
FormulaC37H39N3O14
Molecular Weight749.72
CAS Number1204819-90-8
SMILESOC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(NCCN5C(C=CC5=O)=O)=O)(O)C[C@@H]4O[C@H]6C[C@]7([H])N8[C@]([C@H](OCC8)OC)([H])O[C@]7([H])[C@@H](O6)C
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC