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Mal-Val-Lys-PAB-MMAE

Catalog No.: A41525
Drug-Linker Conjugate for ADC
Mal-Val-Lys-PAB-MMAE is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound integrates a potent tubulin inhibitor, MMAE, with a stable linker (Mal-Val-Lys-PAB), enabling targeted delivery of chemotherapeutic agents. Mal-Val-Lys-PAB-MMAE is suitable for the synthesis of ADCs, facilitating research in cancer therapeutics and enhancing the efficacy of targeted therapies.
Mal-Val-Lys-PAB-MMAE 2435608-81-2 Drug-Linker Conjugate for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-Val-Lys-PAB-MMAE is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound integrates a potent tubulin inhibitor, MMAE, with a stable linker (Mal-Val-Lys-PAB), enabling targeted delivery of chemotherapeutic agents. Mal-Val-Lys-PAB-MMAE is suitable for the synthesis of ADCs, facilitating research in cancer therapeutics and enhancing the efficacy of targeted therapies.
Product Information
Catalog NumA41525
FormulaC68H106N10O14
Molecular Weight1287.63
CAS Number2435608-81-2
SMILESO[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCCN)NC([C@H](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC