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MC-betaglucuronide-MMAE-1

Catalog No.: A41322
Drug-Linker Conjugate for ADC
MC-betaglucuronide-MMAE-1 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound exhibits potent antitumor activity through the action of MMAE, a tubulin polymerization inhibitor. The incorporation of the cleavable ADC linker MC-betaglucuronide enables targeted delivery and release of MMAE in tumor cells, enhancing therapeutic efficacy in cancer research.
MC-betaglucuronide-MMAE-1 1703778-92-0 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
1mg
$415.00
In stock
5mg
$970.00
In stock
10mg
$1,530.00
In stock
25mg
$2,755.00
In stock
50mg
$3,770.00
In stock
100mg
$5,170.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMC-betaglucuronide-MMAE-1 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound exhibits potent antitumor activity through the action of MMAE, a tubulin polymerization inhibitor. The incorporation of the cleavable ADC linker MC-betaglucuronide enables targeted delivery and release of MMAE in tumor cells, enhancing therapeutic efficacy in cancer research.
Product Information
Catalog NumA41322
FormulaC66H98N8O20
Molecular Weight1323.53
CAS Number1703778-92-0
SMILESO[C@H]1[C@H](O)[C@@H](O)[C@H](OC2=C(NC(CCNC(CCCCCN3C(C=CC3=O)=O)=O)=O)C=C(COC(N(C)[C@@H](C(C)C)C(N[C@H](C(N(C)[C@@H]([C@H](CC)C)[C@H](OC)CC(N4[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C5=CC=CC=C5)=O)CCC4)=O)=O)C(C)C)=O)=O)C=C2)O[C@@H]1C(O)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC