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MC-betaglucuronide-MMAE-2

Catalog No.: A41550
Drug-Linker Conjugate for ADC
MC-betaglucuronide-MMAE-2 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs), leveraging the potent antitumor activity of MMAE, a known tubulin polymerization inhibitor. The conjugate features a cleavable linker, MC-betaglucuronide, facilitating targeted delivery and release of the cytotoxic agent within tumor cells. This compound is suitable for research applications in oncology and cancer therapeutics, specifically in studies focused on ADC efficacy and mechanism of action.
MC-betaglucuronide-MMAE-2 1703778-81-7 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
1mg
$280.00
In stock
5mg
$720.00
In stock
10mg
$1,175.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMC-betaglucuronide-MMAE-2 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs), leveraging the potent antitumor activity of MMAE, a known tubulin polymerization inhibitor. The conjugate features a cleavable linker, MC-betaglucuronide, facilitating targeted delivery and release of the cytotoxic agent within tumor cells. This compound is suitable for research applications in oncology and cancer therapeutics, specifically in studies focused on ADC efficacy and mechanism of action.
Product Information
Catalog NumA41550
FormulaC63H93N9O20
Molecular Weight1296.46
CAS Number1703778-81-7
SMILESO[C@H]1[C@H](O)[C@@H](O)[C@H](OC2=C(NC(CCNC([C@H](CN)N3C(C=CC3=O)=O)=O)=O)C=C(COC(N(C)[C@@H](C(C)C)C(N[C@H](C(N(C)[C@@H]([C@H](CC)C)[C@H](OC)CC(N4[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C5=CC=CC=C5)=O)CCC4)=O)=O)C(C)C)=O)=O)C=C2)O[C@@H]1C(O)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC