MC-DM1

Catalog No.: A41382
Drug-Linker Conjugate for ADC
MC-DM1 is a drug-linker conjugate that combines the potent microtubule-disrupting agent DM1 with the stable linker MC, designed for application in antibody-drug conjugates (ADCs). This compound effectively facilitates targeted delivery of cytotoxic agents to malignant cells, thereby enhancing therapeutic efficacy while minimizing off-target effects. MC-DM1 is suitable for research focused on cancer treatment and the development of next-generation ADCs.
Grouped product items
Size Price Stock Qty
1mg
$255.00
In stock
5mg
$615.00
In stock
10mg
$940.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMC-DM1 is a drug-linker conjugate that combines the potent microtubule-disrupting agent DM1 with the stable linker MC, designed for application in antibody-drug conjugates (ADCs). This compound effectively facilitates targeted delivery of cytotoxic agents to malignant cells, thereby enhancing therapeutic efficacy while minimizing off-target effects. MC-DM1 is suitable for research focused on cancer treatment and the development of next-generation ADCs.
Product Information
Catalog NumA41382
FormulaC42H55ClN4O12
Molecular Weight843.36
CAS Number1375089-56-7
SMILESC[C@]1([C@H](CC(N(C(C=C(C2)C=C3OC)=C3Cl)C)=O)OC([C@H](C)N(C)C(CCCCCN(C4=O)C(C=C4)=O)=O)=O)[C@@]([C@@H]([C@](OC5=O)([H])C[C@]([C@@H](/C=C/C=C2\C)OC)(N5)O)C)([H])O1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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