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MC-GGFG-3-Methylenecyclobutyl-Exatecan

Catalog No.: A41593
Drug-Linker Conjugate for ADC
MC-GGFG-3-Methylenecyclobutyl-Exatecan functions as a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound combines the potent cytotoxic properties of Exatecan with a specialized linker, facilitating targeted delivery of therapeutics to cancer cells. It is invaluable for researchers involved in ADC synthesis and development, contributing to advancements in targeted cancer therapies.
MC-GGFG-3-Methylenecyclobutyl-Exatecan 3109352-90-8 Drug-Linker Conjugate for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMC-GGFG-3-Methylenecyclobutyl-Exatecan functions as a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound combines the potent cytotoxic properties of Exatecan with a specialized linker, facilitating targeted delivery of therapeutics to cancer cells. It is invaluable for researchers involved in ADC synthesis and development, contributing to advancements in targeted cancer therapies.
Product Information
Catalog NumA41593
FormulaC57H62FN9O13
Molecular Weight1100.15
CAS Number3109352-90-8
SMILESO=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@H](C3CC(C3)=C)C(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O)=O
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC