MC-GGFG-DX8951

Catalog No.: A18781

MC-GGFG-DX8951

MC-GGFG-DX8951 Chemical Structure

CAS NO. 1600418-29-8

MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker.

Availability: In stock

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1 mg

Regular Price: $320.00

Special Price $256.00

5 mg

Regular Price: $960.00

Special Price $768.00

10 mg

Regular Price: $1,600.00

Special Price $1,280.00

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Biological Activity

MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.56 mL 52.8 mL 105.6 mL
0.5 mM 2.11 mL 10.56 mL 21.12 mL
1 mM 1.06 mL 5.28 mL 10.56 mL
5 mM 0.21 mL 1.06 mL 2.11 mL

*The above data is based on the productmolecular weight 946.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18781
CAS No. 1600418-29-8
Formula C49H51FN8O11
M. Wt 946.99
Purity >98%
Synonyms MC-GGFG-DX8951; MC-GGFG-DX-8951; MC-GGFG-DX 8951; MC-GGFG-DX.
SMILES O=C1[[email protected]](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[[email protected]@H]5NC(CNC([[email protected]](CC7=CC=CC=C7)NC(CNC(CNC(CCCCCN8C(C=CC8=O)=O)=O)=O)=O)=O)=O)C(C)=C(F)C=C6N=C4C3=C2)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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