MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan

Name: MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
Brand: Adooq Bioscience
SKU: A41334
Rating: 5 (288 reviews)

Catalog No.: A41334

Drug-Linker Conjugate for ADC

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound features Exatecan, a potent inhibitor of DNA Topoisomerase I with an IC50 of 2.2 μM, which interferes with DNA replication and induces apoptosis in cancer cells. Its application in ADCs allows for targeted delivery of cytotoxic agents to tumor cells, enhancing therapeutic efficacy while minimizing off-target effects.

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MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan 2414254-51-4 Drug-Linker Conjugate for ADC

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Grouped product items
Size	Price	Stock
1mg	$600.00	In stock
5mg	$1,560.00	In stock
10mg	$2,520.00	In stock
25mg	$3,780.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description

Product Information

Catalog Num	A41334
Formula	C55H60FN9O13
Molecular Weight	1074.12
CAS Number	2414254-51-4
SMILES	O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@H](C3CC3)C(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O)=O
Synonyms	SHR-A1811 Drug-linker

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