MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan

Name: MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan
Brand: Adooq Bioscience
SKU: A41465
Rating: 5 (288 reviews)

Catalog No.: A41465

Drug-Linker Conjugate for ADC

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It integrates Exatecan, a potent inhibitor of DNA Topoisomerase I, with an IC50 value of 2.2 μM. This conjugate enables targeted delivery of cytotoxic agents to cancer cells, enhancing therapeutic efficacy while minimizing off-target effects. It is suitable for research involving ADC development and optimization in cancer therapeutics.

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MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan 2414254-52-5 Drug-Linker Conjugate for ADC

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Grouped product items
Size	Price	Stock
1mg	$600.00	In stock
5mg	$1,970.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description

Product Information

Catalog Num	A41465
Formula	C55H60FN9O13
Molecular Weight	1074.12
CAS Number	2414254-52-5
SMILES	O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@@H](C3CC3)C(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O)=O

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