MC-VA-PAB-Exatecan

Name: MC-VA-PAB-Exatecan
Brand: Adooq Bioscience
SKU: A41318
Rating: 5 (288 reviews)

Catalog No.: A41318

Drug-Linker Conjugate for ADC

MC-VA-PAB-Exatecan is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It combines a peptide linker, MC-VA-PAB, with Exatecan, a potent inhibitor of DNA topoisomerase I, to enhance therapeutic efficacy. Synthesis of MC-VA-PAB-Exatecan-based ADCs demonstrates significant antitumor activity, making it a valuable tool for cancer research and drug development.

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MC-VA-PAB-Exatecan 2680543-57-9 Drug-Linker Conjugate for ADC

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Grouped product items
Size	Price	Stock
2mg	$165.00	In stock
5mg	$285.00	In stock
10mg	$435.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	MC-VA-PAB-Exatecan is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It combines a peptide linker, MC-VA-PAB, with Exatecan, a potent inhibitor of DNA topoisomerase I, to enhance therapeutic efficacy. Synthesis of MC-VA-PAB-Exatecan-based ADCs demonstrates significant antitumor activity, making it a valuable tool for cancer research and drug development.

Product Information

Catalog Num	A41318
Formula	C50H54FN7O11
Molecular Weight	948.00
CAS Number	2680543-57-9
SMILES	O=C(C=CC1=O)N1CCCCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O

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