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MC-VA-PABC-MMAE

Catalog No.: A41323
Drug-Linker Conjugate For ADC
MC-VA-PABC-MMAE is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound integrates the linker peptide MC-VA-PABC with the potent tubulin polymerization inhibitor MMAE, facilitating targeted delivery of the cytotoxic agent. It plays a crucial role in enhancing the therapeutic efficacy of ADCs in cancer research by selectively delivering MMAE to tumor cells while minimizing systemic toxicity.
MC-VA-PABC-MMAE 1818864-51-5 Drug-Linker Conjugate For ADC
Grouped product items
Size Price Stock Qty
1mg
$130.00
In stock
5mg
$215.00
In stock
10mg
$345.00
In stock
25mg
$560.00
In stock
50mg
$820.00
In stock
100mg
$1,200.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMC-VA-PABC-MMAE is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound integrates the linker peptide MC-VA-PABC with the potent tubulin polymerization inhibitor MMAE, facilitating targeted delivery of the cytotoxic agent. It plays a crucial role in enhancing the therapeutic efficacy of ADCs in cancer research by selectively delivering MMAE to tumor cells while minimizing systemic toxicity.
Product Information
Catalog NumA41323
FormulaC65H99N9O14
Molecular Weight1230.53
CAS Number1818864-51-5
SMILESC[C@@H](C(N[C@H](C)[C@H](C1=CC=CC=C1)O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](C)NC([C@H](C(C)C)NC(CCCCCN(C4=O)C(C=C4)=O)=O)=O)=O)=O)=O)=O)=O)OC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC