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Biological Activity
MC-Val-Cit-PAB-vinblastine is a drug-linker conjugate for ADC with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 7.32 mL | 36.59 mL | 73.17 mL |
| 0.5 mM | 1.46 mL | 7.32 mL | 14.63 mL |
| 1 mM | 0.73 mL | 3.66 mL | 7.32 mL |
| 5 mM | 0.15 mL | 0.73 mL | 1.46 mL |
*The above data is based on the productmolecular weight 1366.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18502 |
|---|---|
| CAS No. | 2055896-92-7 |
| Formula | C74H97N10O15 |
| M. Wt | 1366.62 |
| Purity | >98% |
| SMILES | CC[[email protected]@]12[[email protected]@]3([H])[[email protected]]4(CCN3CC=C2)[[email protected]](N(C)C5=CC(OC)=C([[email protected]@]6(C7=C(CC[[email protected]@+]8(CC9=CC=C(NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCCCCN%10C(C=CC%10=O)=O)=O)=O)=O)C=C9)C[[email protected]@](C[[email protected]](CC)(O)C8)([H])C6)C%11=CC=CC=C%11N7)C(OC)=O)C=C45)([H])[[email protected]](C(OC)=O)(O)[[email protected]@H]1OC(C)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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