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MC-VC-PAB-Cyclohexanediamine-Thailanstatin A

Catalog No.: A37813
Drug-linker Conjugates for ADC
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A functions as a drug-linker conjugate specifically designed for antibody-drug conjugate (ADC) applications. This compound combines the potent cytotoxic properties of Thailanstatin A with a cleavable linker (MC-vc-PAB), facilitating targeted delivery and release of the drug within cancer cells. It is suitable for ADC synthesis and can be utilized in research focused on targeted cancer therapies and improved therapeutic index.
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A 1609108-96-4 Drug-linker Conjugates for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMC-VC-PAB-Cyclohexanediamine-Thailanstatin A functions as a drug-linker conjugate specifically designed for antibody-drug conjugate (ADC) applications. This compound combines the potent cytotoxic properties of Thailanstatin A with a cleavable linker (MC-vc-PAB), facilitating targeted delivery and release of the drug within cancer cells. It is suitable for ADC synthesis and can be utilized in research focused on targeted cancer therapies and improved therapeutic index.
Product Information
Catalog NumA37813
FormulaC63H91N9O16
Molecular Weight1230.45
CAS Number1609108-96-4
SMILESO[C@H]1[C@@]2(C[C@H](O[C@@H]1/C=C/C(C)=C/C[C@H]3[C@H](C[C@H]([C@H](O3)C)NC(/C=C\[C@H](C)OC(C)=O)=O)C)CC(N[C@@H]4CC[C@H](CC4)NC(OCC5=CC=C(C=C5)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)=O)=O)CO2
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Calculate the dilution required to prepare a stock solution.
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC