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MC-VC-PAB-Daptomycin

Catalog No.: A41480
Drug-Linker Conjugates for ADC
MC-VC-PAB-Daptomycin is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). It comprises Daptomycin, a lipopeptide antibiotic known for its potent antibacterial activity, linked through a specialized polymeric bridge. This conjugate facilitates targeted delivery of therapeutic agents, enhancing the efficacy of ADCs in treating various cancers and bacterial infections. Its unique structure allows for selective action while minimizing off-target effects, making it a valuable tool in drug development and research applications.
MC-VC-PAB-Daptomycin 1639428-78-6 Drug-Linker Conjugates for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMC-VC-PAB-Daptomycin is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). It comprises Daptomycin, a lipopeptide antibiotic known for its potent antibacterial activity, linked through a specialized polymeric bridge. This conjugate facilitates targeted delivery of therapeutic agents, enhancing the efficacy of ADCs in treating various cancers and bacterial infections. Its unique structure allows for selective action while minimizing off-target effects, making it a valuable tool in drug development and research applications.
Product Information
Catalog NumA41480
FormulaC101H139N23O34
Molecular Weight2219.32
CAS Number1639428-78-6
SMILESO=C(N[C@H](CC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@H](C(NCC(N[C@H](C(N[C@@](C(N[C@@H](C(N[C@H]1CC(O)=O)=O)C)=O)([H])CC(O)=O)=O)CCCNC(OCC2=CC=C(C=C2)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)=O)=O)=O)[C@H](OC([C@](NC([C@](NC([C@@](NC(CNC1=O)=O)([H])CO)=O)([H])[C@H](C)CC(O)=O)=O)([H])CC(C(C=CC=C4)=C4N)=O)=O)C)=O)=O)[C@@H](NC(CCCCCCCCC)=O)CC5=CNC6=CC=CC=C56
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC