• Sign In
  • FAQ
  • Create an Account
Currency
USD currency flagUSD
Toggle Nav
My Cart
Menu
Account
Settings
Currency
USD currency flagUSD

MC-VC-PABC-C6-α-Amanitin

Catalog No.: A41417
Drug-Linker Conjugate for ADC
MC-VC-PABC-C6-α-Amanitin is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, featuring the potent RNA polymerase IIα inhibitor α-Amanitin linked through a MC-VC-PABC-C6 linker. This compound exhibits significant cytotoxic activity against cancer cells by disrupting transcriptional processes. It is an essential tool for researchers focusing on targeted cancer therapies and ADC development.
MC-VC-PABC-C6-α-Amanitin 2922514-69-8 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
100µg
$2,120.00
In stock
500µg
$5,295.00
In stock
1mg
$8,800.00
In stock
Bulk Size
Bulk Discount
Bulk Inquiry
Notify me when the price drops
Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMC-VC-PABC-C6-α-Amanitin is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, featuring the potent RNA polymerase IIα inhibitor α-Amanitin linked through a MC-VC-PABC-C6 linker. This compound exhibits significant cytotoxic activity against cancer cells by disrupting transcriptional processes. It is an essential tool for researchers focusing on targeted cancer therapies and ADC development.
Product Information
Catalog NumA41417
FormulaC74H105N17O22S
Molecular Weight1616.79
CAS Number2922514-69-8
SMILESO=[S@](C[C@@](NC(CNC([C@@]([C@@H](C)CC)([H])N1)=O)=O)([H])C(N[C@@](C(N(C[C@H](O)C2)[C@]2([H])C3=O)=O)([H])CC(N)=O)=O)C4=C(C[C@](C(NCC1=O)=O)([H])NC([C@](N3)([H])[C@@H](C)[C@@H](O)CO)=O)C5=CC=C(OCCCCCCNC(OCC6=CC=C(NC([C@@H](CCCNC(N)=O)NC([C@@H](C(C)C)NC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)C=C6)=O)C=C5N4
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC