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$0.00 Biological Activity
Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.45 mL | 62.27 mL | 124.53 mL |
| 0.5 mM | 2.49 mL | 12.45 mL | 24.91 mL |
| 1 mM | 1.25 mL | 6.23 mL | 12.45 mL |
| 5 mM | 0.25 mL | 1.25 mL | 2.49 mL |
*The above data is based on the productmolecular weight 803. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18379 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 803 |
| Formula | C45H46N4O6S2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2042211-12-9 |
| SMILES | O=C(NS(=O)(C1=CC=C(NCCSC2=CC=CC=C2)C([N+]([O-])=O)=C1)=O)C3=CC=C(NC(C(C=C4)=CC=C4C(C5=C(C)C=C(C(C)(C)CCC6(C)C)C6=C5)=C)=O)C=C3 |
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