Mer/c-Met-IN-1

Catalog No.: A32560
Mer/c-met Inhibitor
Mer/c-Met-IN-1 is a potent dual inhibitor targeting Mer and c-Met with IC50 values of 1 nM and 19 nM, respectively. This compound effectively inhibits cancer cell proliferation and migration while inducing apoptosis. Mer/c-Met-IN-1 is valuable for research into various cancers, including colon cancer, providing insights into therapeutic strategies and mechanisms of action.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMer/c-Met-IN-1 is a potent dual inhibitor targeting Mer and c-Met with IC50 values of 1 nM and 19 nM, respectively. This compound effectively inhibits cancer cell proliferation and migration while inducing apoptosis. Mer/c-Met-IN-1 is valuable for research into various cancers, including colon cancer, providing insights into therapeutic strategies and mechanisms of action.
Product Information
Catalog NumA32560
FormulaC38H38FN7O4
Molecular Weight675.75
CAS Number3062159-91-2
SMILESCN1CCN(CC1)C2=CC(NC3=NC(OC4=CC=C(C=C4)NC(C5=CN(C=C(C5=O)C6=CC=C(C=C6)F)CC7CCCO7)=O)=CC=N3)=CC=C2
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