MGCD-265 (Glesatinib)

Catalog No.: A10587
c-Met inhibitor
MGCD265 is a multitargeted tyrosine kinase inhibitor that binds to and inhibits the phosphorylation of several RTKs, including the c-Met receptor (HGFR); the Tek/Tie-2 receptor; VEGFR types 1, 2, and 3; and MST1R.
Grouped product items
Product Name Price Stock Qty
MGCD-265 5mg
Special Price $96.00 Regular Price $120.00
In stock
MGCD-265 10mg
Special Price $176.00 Regular Price $220.00
In stock
MGCD-265 50mg
Special Price $520.00 Regular Price $650.00
In stock
MGCD-265 100mg
Special Price $784.00 Regular Price $980.00
In stock
MGCD-265 10mM * 1mL in DMSO
Special Price $171.20 Regular Price $214.00
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Biological Activity
Discription MGCD265 is a multitargeted tyrosine kinase inhibitor that binds to and inhibits the phosphorylation of several RTKs, including the c-Met receptor (HGFR); the Tek/Tie-2 receptor; VEGFR types 1, 2, and 3; and MST1R.
Targets
Target Value
Product Information
Catalog Num A10587
Formula C26H20FN5O2S2
Molecular Weight 517.6
CAS Number 875337-44-3
SMILES CN1C=C(N=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(=O)CC5=CC=CC=C5)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 99 mg/mL (191.26 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.32 mL 96.6 mL 193.2 mL
0.5 mM 3.86 mL 19.32 mL 38.64 mL
1 mM 1.93 mL 9.66 mL 19.32 mL
5 mM 0.39 mL 1.93 mL 3.86 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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