Biological Activity
MI-773 is an orally available MDM2 antagonist with Ki of 0.88 nM.
Targets
p53 | MDM2 | |||
N/A | 0.88 nM |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.78 mL | 88.89 mL | 177.78 mL |
0.5 mM | 3.56 mL | 17.78 mL | 35.56 mL |
1 mM | 1.78 mL | 8.89 mL | 17.78 mL |
5 mM | 0.36 mL | 1.78 mL | 3.56 mL |
*The above data is based on the productmolecular weight 562.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15440 |
---|---|
Actions | Inhibitor |
M. Wt | 562.5 |
Formula | C29H34Cl2FN3O3 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1303607-60-4 |
Synonyms | SAR405838,MI 773, MI773 |
SMILES | CC(C)(C)C[[email protected]]1[[email protected]@]2([[email protected]]([[email protected]@H](N1)C(=O)NC3CCC(CC3)O)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O |
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