Total item
Cart Subtotal
$0.00 Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order
Biological Activity
MI-773 is an orally available MDM2 antagonist with Ki of 0.88 nM.
Targets
| p53 | MDM2 | |||
| N/A | 0.88 nM |
| In vitro | DMSO | 93 mg/mL (165.33 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 29 mg/mL (51.55 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.78 mL | 88.89 mL | 177.78 mL |
| 0.5 mM | 3.56 mL | 17.78 mL | 35.56 mL |
| 1 mM | 1.78 mL | 8.89 mL | 17.78 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.56 mL |
*The above data is based on the productmolecular weight 562.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15440 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1303607-60-4 |
| Formula | C29H34Cl2FN3O3 |
| M. Wt | 562.5 |
| Purity | >98% |
| Synonyms | SAR405838,MI 773, MI773 |
| SMILES | CC(C)(C)C[C@H]1[C@@]2([C@H]([C@@H](N1)C(=O)NC3CCC(CC3)O)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
Lithocholic acid
Lithocholic acid is a bile acid that acts as a detergent to solubilize fats for absorption.
p53 and MDM2 proteins-interaction-inhibitor chiral
p53 and MDM2 proteins-interaction-inhibitor chiral is an inhibitor of the interaction between p53 and MDM2 proteins.
NSC-207895 (XI-006)
NSC207895 is a cell-permeable benzofuroxan compound that downregulates the p53 negative regulator MDMX protein level in MCF-7, LNCaP, and A…
YH239-EE
YH239-EE is a potent p53-MDM2 antagonist and an apoptosis inducer.
Nutlin 3b
Nutlin 3b is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 uM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison…
RG7112
RG7112 is the first clinical small-molecule MDM2 inhibitor designed to occupy the p53-binding pocket of MDM2.
MDM2 Inhibitor
MDM2 Inhibitor is a cell-permeable boranyl-chalcone exhibiting strong binding to MDM2 and irreversibly disrupts the MDM2/p53 protein complex…
p53 and MDM2 proteins-interaction-inhibitor racemic
p53 and MDM2 proteins-interaction-inhibitor racemic is an inhibitor of the interaction between p53 and MDM2 proteins.
Keywords:buy MI-773 | MI-773 Supplier | purchase | cost | manufacturer | order | distributor | buy 1303607-60-4| 1303607-60-4 Supplier | purchase 1303607-60-4 | 1303607-60-4 cost | 1303607-60-4 manufacturer | order 1303607-60-4 | 1303607-60-4 distributor
Adooq Quality Guarantee
We promise all products perform as described.