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MMAE-PAB(p-glucuronide)-PEG3-aminooxy

Catalog No.: A41563
Drug-Linker Conjugates for ADC
MMAE-PAB(p-glucuronide)-PEG3-aminooxy is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound facilitates targeted delivery of cytotoxic agents, enhancing therapeutic efficacy while minimizing off-target effects. Its unique structure allows for stable attachment to antibodies, making it suitable for research applications in cancer therapy and drug development.
MMAE-PAB(p-glucuronide)-PEG3-aminooxy 1835250-20-8 Drug-Linker Conjugates for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMMAE-PAB(p-glucuronide)-PEG3-aminooxy is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound facilitates targeted delivery of cytotoxic agents, enhancing therapeutic efficacy while minimizing off-target effects. Its unique structure allows for stable attachment to antibodies, making it suitable for research applications in cancer therapy and drug development.
Product Information
Catalog NumA41563
FormulaC60H95N7O20
Molecular Weight1234.43
CAS Number1835250-20-8
SMILESC[C@@H](C(N[C@H](C)[C@H](C1=CC=CC=C1)O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC(C(NCCOCCOCCON)=O)=C3O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)C(O)=O)=O)=O)=O)=O)OC
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This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC