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MMAE-SMCC

Catalog No.: A41364
Drug-Linker Conjugate for ADC
MMAE-SMCC is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It consists of the potent mitotic inhibitor Monomethyl Auristatin E (MMAE) conjugated through a stable SMCC linker. This compound targets microtubule dynamics, effectively inhibiting cell division in cancer cells. MMAE-SMCC serves as a valuable tool in the development of targeted cancer therapies, allowing for selective delivery of cytotoxic agents to tumor cells.
MMAE-SMCC 2021179-11-1 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
1mg
$300.00
In stock
5mg
$810.00
In stock
10mg
$1,310.00
In stock
25mg
$1,950.00
In stock
50mg
$2,565.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMMAE-SMCC is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It consists of the potent mitotic inhibitor Monomethyl Auristatin E (MMAE) conjugated through a stable SMCC linker. This compound targets microtubule dynamics, effectively inhibiting cell division in cancer cells. MMAE-SMCC serves as a valuable tool in the development of targeted cancer therapies, allowing for selective delivery of cytotoxic agents to tumor cells.
Product Information
Catalog NumA41364
FormulaC58H89N7O14S
Molecular Weight1140.43
CAS Number2021179-11-1
SMILESO[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@@]([C@@H](C)CC)([H])N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(CCSC(C3)C(N(CC4CCC(C(ON5C(CCC5=O)=O)=O)CC4)C3=O)=O)=O)=O)=O)=O)OC)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC