Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order

Nilotinib (AMN-107)

Catalog No.: A10644

Bcr-Abl inhibitor

Nilotinib (AMN-107)

Nilotinib (AMN-107) Chemical Structure

CAS NO. 641571-10-0

Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.

Availability: In stock

Package Price Qty
100 mg
200 mg
10mM * 1mL in DMSO
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Rami Shinnawi, .et al. Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters, Stem Cell Reports, 2015, Oct 13; 5(4): 582-596 PMID: 26372632
  • Tetsuya Saita, .et al. Preparation of Antibodies and Development of an Enzyme-Linked Immunosorbent Assay for the Tyrosine Kinase Inhibitors Lapatinib and Nilotinib., Biol Pharm Bull. , 2015, 38(10):1652-7 PMID: 26424026

Biological Activity

Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.
Bcr-Abl (Murine myeloid progenitor cells)
<30 nM
In vitro (25°C) DMSO 26 mg/mL (49.09 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+30% PEG 300+5% Tween 80+ddH2O 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.89 mL 94.43 mL 188.86 mL
0.5 mM 3.78 mL 18.89 mL 37.77 mL
1 mM 1.89 mL 9.44 mL 18.89 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 529.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10644
Actions Inhibitor
CAS No. 641571-10-0
Formula C28H22F3N7O
M. Wt 529.5
Purity >98%
Synonyms AMN107

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Nilotinib (AMN-107) | Nilotinib (AMN-107) Supplier | purchase | cost | manufacturer | order | distributor | buy 641571-10-0| 641571-10-0 Supplier | purchase 641571-10-0 | 641571-10-0 cost | 641571-10-0 manufacturer | order 641571-10-0 | 641571-10-0 distributor