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Nilotinib (AMN-107)


Bcr-Abl inhibitor

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Catalog No. A10644

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Nilotinib (AMN-107) 100mg A10644-100

Regular Price: €28.50

Special Price: €25.65

Nilotinib (AMN-107) 200mg A10644-200

Regular Price: €47.50

Special Price: €42.75

Nilotinib (AMN-107) 10mM * 1mL in DMSO A10644-10mM-D

Regular Price: €68.40

Special Price: €61.56

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.

Nilotinib (AMN-107)

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Publications citing Adooq Products
Nilotinib (AMN-107) Citations (2)
  • Rami Shinnawi, .et al. Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters, Stem Cell Reports, 2015, Oct 13; 5(4): 582-596 PMID: 26372632
  • Tetsuya Saita, .et al. Preparation of Antibodies and Development of an Enzyme-Linked Immunosorbent Assay for the Tyrosine Kinase Inhibitors Lapatinib and Nilotinib., Biol Pharm Bull. , 2015, 38(10):1652-7 PMID: 26424026

Chemical Information

Catalog Num A10644
Actions Inhibitor
M. Wt 529.5
Formula C28H22F3N7O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 641571-10-0
Synonyms AMN107

Biological Activity

Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.
Bcr-Abl (Murine myeloid progenitor cells)
<30 nM


Solubility (25°C) * In vitro DMSO 27 mg/mL (50.98 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.89 mL 94.43 mL 188.86mL
0.5 mM 3.78 mL 18.89 mL 37.77 mL
1 mM 1.89 mL 9.44 mL 18.89 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 529.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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