Nilotinib (AMN-107)

Name: Nilotinib (AMN-107)
SKU: A10644
Price: 24 USD
Rating: 5 (2 reviews)

Catalog No.: A10644

Bcr-Abl inhibitor

Adooq's Nilotinib (AMN-107) has been cited by 2 publications

Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.

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Grouped product items
Product Name	Price	Stock
Nilotinib (AMN-107) 100mg	Special Price $24.00 Regular Price $30.00	In stock
Nilotinib (AMN-107) 200mg	Special Price $40.00 Regular Price $50.00	In stock
*Nilotinib (AMN-107) 10mM 1mL in DMSO**	Special Price $57.60 Regular Price $72.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's Nilotinib (AMN-107) has been cited by 2 publications

Rami Shinnawi, .et al. , Stem Cell Reports, 2015, Oct 13; 5(4): 582-596 PMID: 26372632

Tetsuya Saita, .et al. , Biol Pharm Bull. , 2015, 38(10):1652-7 PMID: 26424026

Biological Activity

Discription

Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.

Targets

Target	Value

Product Information

Catalog Num	A10644
Formula	C28H22F3N7O
Molecular Weight	529.5
CAS Number	641571-10-0
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	26 mg/mL (49.09 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+30% PEG 300+5% Tween 80+ddH2O	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.89 mL	94.43 mL	188.86 mL
0.5 mM	3.78 mL	18.89 mL	37.77 mL
1 mM	1.89 mL	9.44 mL	18.89 mL
5 mM	0.38 mL	1.89 mL	3.78 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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