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Nilotinib monohydrochloride monohydrate

Bcr-Abl inhibitor

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Catalog No. A15186

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Nilotinib monohydrochloride monohydrate 200mg A15186-200
Nilotinib monohydrochloride monohydrate 500mg A15186-500
Nilotinib monohydrochloride monohydrate 1000mg A15186-1000

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.

Nilotinib monohydrochloride monohydrate

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Chemical Information

Catalog Num A15186
Actions Inhibitor
M. Wt 583.99
Formula C28H25ClF3N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 923288-90-8
Synonyms AMN-107, Tasigna, AMN107
SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5.O.Cl

Biological Activity

Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.12 mL 85.62 mL 171.24mL
0.5 mM 3.42 mL 17.12 mL 34.25 mL
1 mM 1.71 mL 8.56 mL 17.12 mL
5 mM 0.34 mL 1.71 mL 3.42 mL

*The above data is based on the productmolecular weight 583.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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