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Biological Activity
Ningetinib Tosylate,also known as CT-053Tosylate and DE-120, is a VEGF and PDGF inhibitor potentially for the treatment of wet age-related macular degeneration. CAS: 1394820-69-9 (free base) 1394820-77-9 (tosylate)
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.72 mL | 68.61 mL | 137.21 mL |
| 0.5 mM | 2.74 mL | 13.72 mL | 27.44 mL |
| 1 mM | 1.37 mL | 6.86 mL | 13.72 mL |
| 5 mM | 0.27 mL | 1.37 mL | 2.74 mL |
*The above data is based on the productmolecular weight 728.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17039 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1394820-77-9 |
| Formula | C38H37FN4O8S |
| M. Wt | 728.79 |
| Purity | >98% |
| Synonyms | CT-053 Tosylate, CT-053, DE-120, CT053, DE120, CT 053, DE 120 |
| SMILES | O=C(C1=C(C)N(C)N(C2=CC=CC=C2)C1=O)NC3=CC=C(OC4=CC=NC5=CC(OCC(C)(O)C)=CC=C45)C(F)=C3.CC6=CC=C(S(=O)(O)=O)C=C6 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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