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Ningetinib Tosylate

Catalog No.: A17039

VEGF and PDGF inhibitor

Ningetinib Tosylate

Ningetinib Tosylate Chemical Structure

CAS NO. 1394820-77-9

Ningetinib Tosylate,also known as CT-053Tosylate and DE-120, is a VEGF and PDGF inhibitor potentially for the treatment of wet age-related macular degeneration. CAS: 1394820-69-9 (free base) 1394820-77-9 (tosylate)

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
50 mg
$780.00
100 mg
$1,320.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Ningetinib Tosylate,also known as CT-053Tosylate and DE-120, is a VEGF and PDGF inhibitor potentially for the treatment of wet age-related macular degeneration. CAS: 1394820-69-9 (free base) 1394820-77-9 (tosylate)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.72 mL 68.61 mL 137.21 mL
0.5 mM 2.74 mL 13.72 mL 27.44 mL
1 mM 1.37 mL 6.86 mL 13.72 mL
5 mM 0.27 mL 1.37 mL 2.74 mL

*The above data is based on the productmolecular weight 728.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17039
Actions Inhibitor
CAS No. 1394820-77-9
Formula C38H37FN4O8S
M. Wt 728.79
Purity >98%
Synonyms CT-053 Tosylate, CT-053, DE-120, CT053, DE120, CT 053, DE 120
SMILES O=C(C1=C(C)N(C)N(C2=CC=CC=C2)C1=O)NC3=CC=C(OC4=CC=NC5=CC(OCC(C)(O)C)=CC=C45)C(F)=C3.CC6=CC=C(S(=O)(O)=O)C=C6
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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