NMS-0963 is a potent inhibitor of spleen tyrosine kinase (SYK), exhibiting an oral bioavailability and an IC50 value of 3 nM. This compound effectively inhibits the proliferation of BaF3-TEL/SYK cell lines at a concentration of 27 nM, making it a valuable tool for investigating SYK-related pathways in various biological contexts and potential therapeutic applications in diseases involving SYK dysregulation.
NMS-0963 is a potent inhibitor of spleen tyrosine kinase (SYK), exhibiting an oral bioavailability and an IC50 value of 3 nM. This compound effectively inhibits the proliferation of BaF3-TEL/SYK cell lines at a concentration of 27 nM, making it a valuable tool for investigating SYK-related pathways in various biological contexts and potential therapeutic applications in diseases involving SYK dysregulation.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
