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$0.00 Biological Activity
NSC348884 is a nucleolar phosphoprotein that displays several biological activities in ribosome biogenesis, cell proliferation, cytoplasmic/nuclear shuttle transportation, nucleic acid binding, ribonucleic cleavage, and centrosome duplication. NSC 348884 is a putative inhibitor of nucleophosmin (NPM). NSC 348884 inhibits NMP oligomer formation, up-regulates p53 and induces apoptosis.
Targets
| nucleophosmin | ||||
| In vitro | DMSO | 92 mg/mL (144.47 mM) | |
| Water | Insoluble | ||
| Ethanol | 92 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.7 mL | 78.52 mL | 157.04 mL |
| 0.5 mM | 3.14 mL | 15.7 mL | 31.41 mL |
| 1 mM | 1.57 mL | 7.85 mL | 15.7 mL |
| 5 mM | 0.31 mL | 1.57 mL | 3.14 mL |
*The above data is based on the productmolecular weight 636.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13117 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 81624-55-7 |
| Formula | C38H40N10 |
| M. Wt | 636.79 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | NSC 348884, NSC-348884 |
| SMILES | CC1=CC2=C(C=C1)N=C(N2)CN(CCN(CC3=NC4=C(N3)C=C(C=C4)C)CC5=NC6=C(N5)C=C(C=C6)C)CC7=NC8=C(N7)C=C(C=C8)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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