NSC348884

Catalog No.: A13117

nucleophosmin inhibitor

NSC348884 Chemical Structure

CAS NO. 81624-55-7

NSC348884 is a nucleolar phosphoprotein that displays several biological activities in ribosome biogenesis, cell proliferation, cytoplasmic/nuclear shuttle transportation, nucleic acid binding, ribonucleic cleavage, and centrosome duplication. NSC 348884 is a putative inhibitor of nucleophosmin (NPM). NSC 348884 inhibits NMP oligomer formation, up-regulates p53 and induces apoptosis.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$125.00
25 mg
$250.00
50 mg
$450.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NSC348884 is a nucleolar phosphoprotein that displays several biological activities in ribosome biogenesis, cell proliferation, cytoplasmic/nuclear shuttle transportation, nucleic acid binding, ribonucleic cleavage, and centrosome duplication. NSC 348884 is a putative inhibitor of nucleophosmin (NPM). NSC 348884 inhibits NMP oligomer formation, up-regulates p53 and induces apoptosis.
Targets
nucleophosmin
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.7 mL 78.52 mL 157.04 mL
0.5 mM 3.14 mL 15.7 mL 31.41 mL
1 mM 1.57 mL 7.85 mL 15.7 mL
5 mM 0.31 mL 1.57 mL 3.14 mL

*The above data is based on the productmolecular weight 636.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13117
Actions Inhibitor
M. Wt 636.79
Formula C38H40N10
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 81624-55-7
Synonyms NSC 348884, NSC-348884
SMILES CC1=CC2=C(C=C1)N=C(N2)CN(CCN(CC3=NC4=C(N3)C=C(C=C4)C)CC5=NC6=C(N5)C=C(C=C6)C)CC7=NC8=C(N7)C=C(C=C8)C

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