NSC59984

Catalog No.: A13413
P53 Activator
NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. The EC50 of NSC59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38 uM for p53-null HCT116 cells.
Grouped product items
Product Name Price Stock Qty
NSC59984 5mg
Special Price $88.00 Regular Price $110.00
In stock
NSC59984 10mg
Special Price $152.00 Regular Price $190.00
In stock
NSC59984 25mg
Special Price $320.00 Regular Price $400.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. The EC50 of NSC59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38 uM for p53-null HCT116 cells.
Targets
Target Value
Product Information
Catalog Num A13413
Formula C12H15N3O4
Molecular Weight 265.27
CAS Number 803647-40-7
SMILES CN1CCN(CC1)C(=O)C=CC2=CC=C(O2)[N+](=O)[O-]
Synonyms NSC 59984, NSC-59984
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 48 mg/mL (180.94 mM)
Water Insoluble
Ethanol 48 mg/mL (180.94 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.7 mL 188.49 mL 376.97 mL
0.5 mM 7.54 mL 37.7 mL 75.39 mL
1 mM 3.77 mL 18.85 mL 37.7 mL
5 mM 0.75 mL 3.77 mL 7.54 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy NSC59984 | NSC59984 Supplier | purchase NSC59984 | NSC59984 cost | NSC59984 manufacturer | order NSC59984 | NSC59984 distributor | buy 803647-40-7 | 803647-40-7 Supplier | purchase 803647-40-7 | 803647-40-7 cost | 803647-40-7 manufacturer | order 803647-40-7 | 803647-40-7 distributor