Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order

NVP-BAW2881

Catalog No.: A12693

VEGFR inhibitor

NVP-BAW2881

NVP-BAW2881 Chemical Structure

CAS NO. 861875-60-7

NVP-BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.

Availability: In stock

Package Price Qty
5 mg
$72.00
10 mg
$122.00
25 mg
$216.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NVP-BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.
Targets
Target Value
TIE-2
hVEGFR2IC50: 9nM
C-Raf-1IC50: 24nM
B-RAFV599EIC50: 76nM
c-AblIC50: 99nM
mVEGF2IC50: 165nM
RETIC50: 410nM
hVEGFR3IC50: 420nM
hVEGFR1IC50: 820nM
c-KITIC50: 2.5μM
In vitro DMSO 76 mg/mL (179.08 mM)
Water Insoluble
Ethanol 18 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.58 mL 117.89 mL 235.79 mL
0.5 mM 4.72 mL 23.58 mL 47.16 mL
1 mM 2.36 mL 11.79 mL 23.58 mL
5 mM 0.47 mL 2.36 mL 4.72 mL

*The above data is based on the productmolecular weight 424.1147. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12693
Actions Inhibitor
CAS No. 861875-60-7
Formula C22H15F3N4O2
M. Wt 424.1147
Purity >98%
Synonyms BAW2881, BAW-2881, BAW 2881, NVP-BAW-2881, NVP-BAW 2881
SMILES O=C(NC1=CC(C(F)(F)F)=CC=C1)C2=CC=CC3=C2C=CC(OC4=CC=NC(N)=N4)=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy NVP-BAW2881 | NVP-BAW2881 Supplier | purchase | cost | manufacturer | order | distributor | buy 861875-60-7| 861875-60-7 Supplier | purchase 861875-60-7 | 861875-60-7 cost | 861875-60-7 manufacturer | order 861875-60-7 | 861875-60-7 distributor
Rewards