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Publications citing Adooq Products
Chemical Information
| Catalog Num | A11507 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 468.94 |
| Formula | C23H25ClN6O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 761437-28-9 |
| Synonyms | TAE226, TAE 226 |
| SMILES | CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCOCC4)OC |
Description |
NVP-TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2(IC50=3.5 nM); 10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Targets |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.32 mL | 106.62 mL | 213.25mL |
| 0.5 mM | 4.26 mL | 21.32 mL | 42.65 mL |
| 1 mM | 2.13 mL | 10.66 mL | 21.32 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.26 mL |
*The above data is based on the productmolecular weight 468.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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