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c-Kit/VEGFR Inhibitor

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Catalog No. A10679

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
OSI-930 5mg A10679-5

Regular Price: $90.00

Special Price: $81.00

OSI-930 25mg A10679-25

Regular Price: $200.00

Special Price: $180.00

OSI-930 50mg A10679-50

Regular Price: $350.00

Special Price: $315.00

OSI-930 100mg A10679-100

Regular Price: $600.00

Special Price: $540.00

OSI-930 10mM * 1mL in DMSO A10679-10mM-D

Regular Price: $139.00

Special Price: $125.10

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

OSI-930 is a potent inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck with IC50 of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM, respectively.


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Chemical Information

Catalog Num A10679
Actions Inhibitor
M. Wt 443.4
Formula C22H16F3N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 728033-96-3
Synonyms OSI930

Biological Activity

OSI-930 is a potent inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck with IC50 of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM, respectively.
Target Value
FLT1IC50: 8nM
KDRIC50: 9nM
CSF-1RIC50: 15nM
LCKIC50: 22nM
C-RafIC50: 41nM
KitIC50: 80nM
FLT3IC50: 1.303μM
PDGFRαIC50: 3.408μM
AblIC50: 4.738μM
PDGFRβIC50: 6.9μM
EGFRIC50: >10μM
AuroraAIC50: >10μM
AxlIC50: >10μM
CDK2/CyclinAIC50: >10μM
IKKβIC50: >10μM
MEK1IC50: >10μM
PDPK1IC50: >10μM
PKBβIC50: >10μM
Tie-2IC50: >10μM


Solubility (25°C) * In vitro DMSO 89 mg/mL (200.7 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (6.76 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.55 mL 112.76 mL 225.53mL
0.5 mM 4.51 mL 22.55 mL 45.11 mL
1 mM 2.26 mL 11.28 mL 22.55 mL
5 mM 0.45 mL 2.26 mL 4.51 mL

*The above data is based on the productmolecular weight 443.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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