P505-15 (PRT062607, BIIB057)

Catalog No.: A11952

Syk inhibitor

P505-15 (PRT062607, BIIB057) Chemical Structure

CAS NO. 1370261-96-3

P505-15 (also known as PRT062607) is a novel, highly selective, and orally bioavailable small molecule SYK inhibitor (SYK IC(50) = 1 nM) with anti-SYK activity that is at least 80-fold greater than its affinity for other kinases.

Availability: In stock

Package Price Qty
5 mg
$100.00
10 mg
$180.00
25 mg
$350.00
50 mg
$600.00
10mM * 1mL in DMSO
$138.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

P505-15 (also known as PRT062607) is a novel, highly selective, and orally bioavailable small molecule SYK inhibitor (SYK IC(50) = 1 nM) with anti-SYK activity that is at least 80-fold greater than its affinity for other kinases.
In vitro (25°C) DMSO 86 mg/mL (200.04 mM)
Water 86 mg/mL (200.04 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.42 mL 127.08 mL 254.16 mL
0.5 mM 5.08 mL 25.42 mL 50.83 mL
1 mM 2.54 mL 12.71 mL 25.42 mL
5 mM 0.51 mL 2.54 mL 5.08 mL

*The above data is based on the productmolecular weight 393.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11952
Actions Inhibitor
M. Wt 393.45
Formula C19H23N9O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1370261-96-3
Synonyms P50515, PRT062607
SMILES CC(=O)O.C1CC[[email protected]]([[email protected]](C1)N)NC2=NC=C(C(=N2)NC3=CC=CC(=C3)N4N=CC=N4)C(=O)N

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