Trusted by 10,000+ Scientists since 2006

Pazopanib (GW-786034)


VEGFR inhibitor

0 Customer Reviews
Catalog No. A11518

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Pazopanib 25mg A11518-25

Regular Price: €61.75

Special Price: €55.58

Pazopanib 50mg A11518-50

Regular Price: €114.00

Special Price: €102.60

Pazopanib 100mg A11518-100

Regular Price: €190.00

Special Price: €171.00

Pazopanib(GW-786034) 10mM * 1mL in DMSO A11518-10mM-D

Regular Price: €66.50

Special Price: €59.85

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit that blocks tumor growth and inhibits angiogenesis.

Pazopanib (GW-786034)

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products
Pazopanib (GW-786034) Citations (3)
  • Koide H, .et al. Substrate-dependent effects of molecular-targeted anticancer agents on activity of organic anion transporting polypeptide 1B1, Xenobiotica, 2018, Oct;48(10):1059-1071 PMID: 29034773
  • Ellawatty WEA, .et al. Organic cation transporter 1 is responsible for hepatocellular uptake of the tyrosine kinase inhibitor pazopanib, Drug Metab Dispos, 2018, Jan;46(1):33-40 PMID: 29089306
  • Fujita KI, .et al. Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites, J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358

Chemical Information

Catalog Num A11518
Actions Inhibitor
M. Wt 437.5
Formula C21H23N7O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 444731-52-6
Synonyms GW 786034, Votrient,GW786034
SMILES CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N

Biological Activity

Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit that blocks tumor growth and inhibits angiogenesis.
Target Value
VEGFR1IC50: 10nM
VEGFR2IC50: 30nM
VEGFR3IC50: 47nM
FGFRIC50: 74nM
c-KitIC50: 140nM
c-FmsIC50: 146nM


Solubility (25°C)* In vitro DMSO 88 mg/mL (201.13 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.86 mL 114.29 mL 228.57mL
0.5 mM 4.57 mL 22.86 mL 45.71 mL
1 mM 2.29 mL 11.43 mL 22.86 mL
5 mM 0.46 mL 2.29 mL 4.57 mL

*The above data is based on the productmolecular weight 437.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Similar product(s)

Keywords:buy Pazopanib (GW-786034) | Pazopanib (GW-786034) Supplier | purchase Pazopanib (GW-786034) | Pazopanib (GW-786034) cost | Pazopanib (GW-786034) manufacturer | order Pazopanib (GW-786034) | Pazopanib (GW-786034) distributor | buy 444731-52-6| 444731-52-6 Supplier | purchase 444731-52-6 | 444731-52-6 cost | 444731-52-6 manufacturer | order 444731-52-6 | 444731-52-6 distributor