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PB089

Catalog No.: A41434
Drug-Linker Conjugates for ADC
PB089 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It features a polyethylene glycol (PEG) unit along with a cleavable linker, which facilitates the delivery of the cytotoxic agent Exatecan to target cells. This compound is valuable for enhancing the therapeutic index of ADCs by improving selectivity and minimizing off-target effects in cancer research.
PB089 2892336-54-6 Drug-Linker Conjugates for ADC
Grouped product items
Size Price Stock Qty
1mg
$705.00
In stock
5mg
$1,970.00
In stock
10mg
$3,360.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPB089 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It features a polyethylene glycol (PEG) unit along with a cleavable linker, which facilitates the delivery of the cytotoxic agent Exatecan to target cells. This compound is valuable for enhancing the therapeutic index of ADCs by improving selectivity and minimizing off-target effects in cancer research.
Product Information
Catalog NumA41434
FormulaC90H133FN12O32
Molecular Weight1914.08
CAS Number2892336-54-6
SMILESO=C(OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN(C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)NC(CCCCCN(C2=O)C(C=C2)=O)=O)=O)=O)=O)N[C@@H]3C(C4=C5CC3)=C(CN6C7=CC([C@@]8(O)CC)=C(COC8=O)C6=O)C7=NC4=CC(F)=C5C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC