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$0.00 Biological Activity
PD166866 is a FGFR1 inhibitor with IC50 value of 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4.
| In vitro (25°C) | DMSO | Warmed: 12 mg/mL (30.27 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 3 mg/mL (7.56 mM) | ||
| In vivo | 4% DMSO+30% PEG 300+2% Tween 80+ddH2O | 3 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.22 mL | 126.12 mL | 252.24 mL |
| 0.5 mM | 5.04 mL | 25.22 mL | 50.45 mL |
| 1 mM | 2.52 mL | 12.61 mL | 25.22 mL |
| 5 mM | 0.5 mL | 2.52 mL | 5.04 mL |
*The above data is based on the productmolecular weight 396.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17161 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 192705-79-6 |
| Formula | C20H24N6O3 |
| M. Wt | 396.44 |
| Purity | >98% |
| Synonyms | PD 166866, PD-166866 |
| SMILES | O=C(NC(C)(C)C)NC1=NC2=NC(N)=NC=C2C=C1C3=CC(OC)=CC(OC)=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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