PD166866

Catalog No.: A17161

FGFR inhibitor

PD166866

PD166866 Chemical Structure

CAS NO. 192705-79-6

PD166866 is a FGFR1 inhibitor with IC50 value of 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$100.00
50 mg
$380.00
100 mg
$670.00
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Biological Activity

PD166866 is a FGFR1 inhibitor with IC50 value of 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4.
In vitro (25°C) DMSO Warmed: 12 mg/mL (30.27 mM)
Water Insoluble
Ethanol Warmed: 3 mg/mL (7.56 mM)
In vivo 4% DMSO+30% PEG 300+2% Tween 80+ddH2O 3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.22 mL 126.12 mL 252.24 mL
0.5 mM 5.04 mL 25.22 mL 50.45 mL
1 mM 2.52 mL 12.61 mL 25.22 mL
5 mM 0.5 mL 2.52 mL 5.04 mL

*The above data is based on the productmolecular weight 396.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17161
Actions Inhibitor
CAS No. 192705-79-6
Formula C20H24N6O3
M. Wt 396.44
Purity >98%
Synonyms PD 166866, PD-166866
SMILES O=C(NC(C)(C)C)NC1=NC2=NC(N)=NC=C2C=C1C3=CC(OC)=CC(OC)=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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