Pexidartinib (PLX3397)

Catalog No.: A15520
CSF1/Kit/FLT3 inhibitor
Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
Grouped product items
Size Price Stock Qty
5mg
$35.00
In stock
10mg
$50.00
In stock
25mg
$80.00
In stock
50mg
$115.00
In stock
100mg
$150.00
In stock
200mg
$205.00
In stock
500mg
$360.00
In stock
1g
$700.00
In stock
2g
$1,180.00
In stock
5g
$2,560.00
In stock
10g
$3,680.00
In stock
20g
$6,620.00
In stock
10mM * 1mL in DMSO
$35.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Adooq Products cited in reputable paper
Adooq's Pexidartinib (PLX3397) has been cited by 5 publications
  • Lu Luo, .et al. , J Neuroinflammation, 2022, Jun 11;19(1):141 PMID: 35690810
  • Sarah R Anderson,, .et al. , bioRxiv, 2022, 01.05.475126
  • Hannah D Mason, .et al. , JCI Insight, 2021, Oct 8;6(19):e149229 PMID: 34428178
  • Chritica Lodder, .et al. , Acta Neuropathol Commun, 2021, Jun 8;9(1):108 PMID: 34103079
  • Anderson SR, .et al. , Cell Rep, 2019, May 14;27(7):2002-2013.e5 PMID: 31091440
  • Biological Activity
    Discription Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A15520
    Formula C20H15ClF3N5
    Molecular Weight 417.81
    CAS Number 1029044-16-3
    SMILES FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F
    Synonyms PLX-3397, PLX 3397
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 71 mg/mL (169.93 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+45% PEG 300+5% Tween 80+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.93 mL 119.67 mL 239.34 mL
    0.5 mM 4.79 mL 23.93 mL 47.87 mL
    1 mM 2.39 mL 11.97 mL 23.93 mL
    5 mM 0.48 mL 2.39 mL 4.79 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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