Pexidartinib (PLX3397)

Catalog No.: A15520

CSF1/Kit/FLT3 inhibitor

Pexidartinib (PLX3397)

Pexidartinib (PLX3397) Chemical Structure

CAS NO. 1029044-16-3

Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $75.00

Special Price $60.00

25 mg

Regular Price: $150.00

Special Price $120.00

50 mg

Regular Price: $240.00

Special Price $192.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
Targets
Kit CSF-1R Flt3
10 nM20 nM160 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.93 mL 119.67 mL 239.34 mL
0.5 mM 4.79 mL 23.93 mL 47.87 mL
1 mM 2.39 mL 11.97 mL 23.93 mL
5 mM 0.48 mL 2.39 mL 4.79 mL

*The above data is based on the productmolecular weight 417.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A15520
Actions Inhibitor
M. Wt 417.81
Formula C20H15ClF3N5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1029044-16-3
Synonyms PLX-3397, PLX 3397
SMILES FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F

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