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PF-04217903 methanesulfonate

c-Met Inhibitor

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Catalog No. A15208

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PF-04217903 methanesulfonate 5mg A15208-5
PF-04217903 methanesulfonate 10mg A15208-10
PF-04217903 methanesulfonate 50mg A15208-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PF-04217903 methanesulfonate is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susceptible to oncogenic mutations (no activity to Y1230C mutant).

PF-04217903 methanesulfonate

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Chemical Information

Catalog Num A15208
Actions Inhibitor
M. Wt 468.49
Formula C20H20N8O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 956906-93-7
Synonyms PF04217903 methanesulfonate, PF 04217903 methanesulfonate

Biological Activity

PF-04217903 methanesulfonate is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susceptible to oncogenic mutations (no activity to Y1230C mutant).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.35 mL 106.73 mL 213.45mL
0.5 mM 4.27 mL 21.35 mL 42.69 mL
1 mM 2.13 mL 10.67 mL 21.35 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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